research field 연구분야
연구성과
Scripps Korea Antibody Institute
research field - SKAI
새로운 10년, 지역산업과 동반성장하는
항체 사이언스의 선도 연구소로 거듭나겠습니다.
항체 사이언스의 선도 연구소로 거듭나겠습니다.
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| Title | Journal | Numbers | Year |
|---|---|---|---|
| PARP Inhibitor Sensitizes BRCA-mutant Pancreatic Cancer to Oxaliplatin by Suppressing the CDK1/BRCA1 Axis | Anticancer Research | DOI: 10.21873/anticanres.16754 | 2023 |
| Development of a neutralization monoclonal antibody with a broad neutralizing efect against SARS-CoV-2 variants | Virology journal | DOI: 10.1186/s12985-023-02230-9 | 2023 |
| Heterologous vaccination utilizing viral vector and protein platforms confers complete protection against SFTSV | Scientific Reports | DOI: 10.1038/s41598-023-35328-9 Free PMC article | 2023 |
| Recombinant measles virus encoding the spike protein of SARS-CoV-2 efficiently induces Th1 responses and neutralizing antibodies that block SARS-CoV-2 variants | Vaccine | DOI: 10.1016/j.vaccine.2023.02.005 | 2023 |
| Recombinant measles virus encoding the spike protein of SARS-CoV-2 efficiently induces Th1 responses and neutralizing antibodies that block SARS-CoV-2 variants | Vaccine | DOI: 10.1016/j.vaccine.2023.02.005 | 2023 |
| Functional Rescue of Inactivating Mutations of the Human Neurokinin 3 Receptor Using Pharmacological Chaperones | International Journal of Molecular Sciences | DOI: 10.3390/ijms23094587 | 2022 |
| An albumin scaffold grafted with an alpha-helical motif delivers therapeutic payloads by modular coiled-coil assembly | International Journal of Biological Macromolecules | DOI: 10.1016/j.ijbiomac.2022.02.040 | 2022 |
| Trafficking-defective mutant PROKR2 cycles between endoplasmic reticulum and Golgi to attenuate endoplasmic reticulum stress | PNAS | DOI: 10.1073/pnas.2102248119 | 2021 |
| Peptides derived from S and N proteins of SARS-CoV-2 induce T cell responses: a proof-of-concept for T-cell vaccines | Frontiers in Microbiology | DOI: 10.3389/fmicb.2021.732450 | 2021 |
| Effective inactivated influenza vaccine for the elderly using a single-stranded RNA-nased adjuvant | Scientific Reports | DOI: 10.1038/s41598-021-91445-3 | 2021 |
| Immunization with RBD-P2 and N protects against SARS-CoV-2 in nonhuman primates | Science Advances | DOI: 10.1126/sciadv.abg7156 | 2021 |
| Systemic delivery of CRISPR/Cas9 to hepatic tumors for cancer treatment using altered tropism of lentiviral vector | Biomatierials | DOI: 10.1016/j.biomaterials.2021.120793 | 2021 |
| 89Zr anti-CD44 immuno-PET monitors CD44 expression on splenic myeloid cells and HT29 colon cancer cells | Scientific Reports | DOI: 10.1038/s41598-021-83496-3 | 2021 |
| Generation and Characterization of Monoclonal Antibodies to the Ogawa Lipopolysaccharide of Vibrio cholerae O1 from Phage-Displayed Human Synthetic Fab Library | Journal of Microbiology and Biotechnology | DOI: 10.4014/jmb.2005.05046 | 2020 |
| Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells | BMC Immunologe | DOI: 10.1186/s12865-020-00347-y | 2020 |
| Inhibition by the atypical antipsychotic risperidone of voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells | European Journal of Pharmacology | DOI: 10.1016/j.ejphar.2020.173027 | 2020 |
| Novel Antibodies Targeting MUC1-C Showed Anti-Metastasis and Growth-Inhibitory Effects on Human Breast Cancer Cells | International Journal of Molecular Sciences | doi: 10.3390/ijms21093258. | 2020 |
| BLI-based Functional assay in phage display benefits the development of a PD-L1-targeting therapeutic antibody | Viruses | doi: 10.3390/v12060684 | 2020 |
| A Novel Anti-PD-L1 Antibody Exhibits Antitumor Effects on Multiple Myeloma in Murine Models via Antibody-Dependent Cellular Cytotoxicity | Journal of Immunology | DOI: 10.4062/biomolther.2020.131 | 2020 |
| Targeting poor proteasomal function with radioiodine eliminates CT26 colon cancer stem cells resistant to bortezomib therapy | Scientific Reports | DOI: 10.1038/s41598-020-71366-3 | 2020 |
| 89Zr Labeled Anti-PD-L1 Antibody PET Monitors Gemcitabine Therapy-Induced Modulation of Tumor PD-L1 Expression | Journal of Nuclear Medicine | DOI: 10.2967 | 2020 |
| Inactivated influenza vaccine formulated with single-stranded RNA-based adjuvant confers mucosal immunity and cross-protection against influenza virus infection | Vaccine | DOI: 10.1016 | 2020 |
| Nanoformulated Sing-stranded RNA-based Adjuvant with a Coordinative Amphiphile as an Effective Stabilizer to induce a Humoral Immune Response by Activation of Antigen-presenting Cells | Angew Chem Int Ed Engl | doi: 10.1002/anie.202002979 | 2020 |
| Activity-expression profiling of glucose-6-phosphate dehydrogenase in tissues of normal and diabetic mice | Biochemical and Biophysical Research Communications | pii: S0006-291X(20)30250-3. | 2020 |
| Perivascular Stem Cells Suppress Inflammasome Activation during Inflammatory Responses in Macrophages | International Journal of Stem Cells | 12(3):419-429. | 2019 |
| Antibody-Based Targeting of Cell Surface GRP94 Specifically Inhibits Cetuximab-Resistant Colorectal Cancer Growth | Biomolecules | 9(11). pii: E681. | 2019 |
| Development of a Theranostic Convergence Bioradiopharmaceutical for Immuno-PET Based Radioimmunotherapy of L1CAM in Cholangiocarcinoma Model | Clinical Cancer Research | 25(20):6148-6159. | 2019 |
| Magnetic Resonance Colonography Enables the Efficacy Assessment of Immune Checkpoint Inhibitors in an Orthotopic Colorectal Cancer Mouse Model | Translational Oncology | 12(9):1264-1270. | 2019 |
| Ultrasensitive NIR-SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation | Advanced Healthcare Materials | 7(4). doi: 10.1002/adhm.201700870. | 2018 |
| Generation of a human monoclonal antibody to cross-reactive material 197 (CRM₁₉₇) and development of a sandwich ELISA for CRM₁₉₇ conjugate vaccines | Journal of Microbiology and Biotechnology | 28(12):2113-2120. | 2018 |
| Generation and Characterization of a Neutralizing Human Monoclonal Antibody to Hepatitis B Virus PreS1 from a Phage-Displayed Human Synthetic Fab Library | Journal of Microbiology and Biotechnology | doi: 10.4014/jmb.1804.03056. | 2018 |
| Emerging Roles of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Immunological Disorders and Cancer | International journal of molecular sciences | 19(4). pii: E1057. | 2018 |
| Inhibition of VEGF-dependent angiogenesis and tumor angiogenesis by an optimized antibody targeting CLEC14a | Molecular Oncology | 12(3):356-372. | 2018 |
| Generation, Diversity Determination, and Application to Antibody Selection of a Human Naïve Fab Library | Molecules and Cells | 40(9):655-66. | 2017 |
| CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis | Scientific Reprots | 7(1):10666 | 2017 |
| A Review of Anti-Angiogenic Targets for Monoclonal Antibody Cancer Therapy | International Journal of Molecular Sciences | 18(8). pii: E1786. | 2017 |
| A human antibody that binds to the sixth Ig-like domain of VCAM-1 blocks lung cancer cell migration in vitro | International Journal of Molecular Sciences | 18(3). pii: E566. | 2017 |
| Ig-like Domain 6 of VCAM-1 is a Potential Therapeutic Target in TNFα-induced Angiogenesis | Experimental and Molecular Medicine | 49(2):e294. | 2017 |
| Adaptor Protein 2 (AP-2) complex is essential for functional axogenesis in hippocampal neurons | axogenesis in hippocampal neurons Scientific Reprots | 7:41620. | 2017 |
| Development of a sandwich enzyme-linked immunosorbent assay for the detection of CD44v3 using exon v3- and v6-specific monoclonal antibody pairs | Journal of Immunological Methods | 436:22-8. | 2016 |
| Therapeutic Targeting of Tetraspanin8 in Epithelial Ovarian Cancer Invasion and Metastasis | Oncogene | 35(34):4540-8. | 2016 |
| Heat shock protein 70-1A is a novel angiogenic regulator | Biochemical and Biophysical Research Communications | 469(2):222-8. | 2016 |
| Generation of a human antibody that inhibits TSPAN8-mediated invasion of metastatic colorectal cancer cells | Biochemical and Biophysical Research Communications | 468(4):774-80. | 2015 |
| Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma | Oncotarget | 6(9):7182-94. | 2015 |
| Human antibodies targeting the C-type lectin domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro | Oncogene | 32(48):5449-57. | 2013 |
| Afamin stimulates osteoclastogenesis and bone resorptio via Gi-coupled receptor and Ca2+/calmodulin-dependent protein kinase (CaMK) pathways | Journal of Endocrinological Investigation | 36(10):876-82. | 2013 |
| Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections | Proceedings of The National Academy of Sciences of The United States of America | 110(37):14966-71. | 2013 |
| Engineering hydrophobic protein-carbohydrate interactions to fine-tune monoclonal antibodies | Journal of the American Chemical Society | 135(26):9723-32. | 2013 |
| Enzymatic production and expression of shRNAmir30 from cDNAs | Genes & Genomics | 35(3):395-403. | 2013 |
| Selecting Agonists from Single Cells Infected with Combinatorial Antibody Libraries | Chemistry & Biology | 20(5):734-41. | 2013 |
| Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells | Proceedings of The National Academy of Sciences of The United States of America | 110(20):8099-104. | 2013 |
| Engineering Cell Surfaces for Orthogonal Selectability | Anagewandte Chemie-International Edition | 52(1):336-40. | 2013 |
| An Antibody to the Sixth Ig-like Domain of VCAM-1 Inhibits Leukocyte Transendothelial Migration without Affecting Adhesion | Journal of Immunology | 189(9):4592-601. | 2012 |
| Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis | Journal of the American Chemical Society | 134(42):17554-63. | 2012 |
| Gremlin-1 Induces BMP-Independent Tumor Cell Proliferation, Migration, and Invasion | PLoS One | 7(4):e35100. | 2012 |
| Cholesterol Secosterol Aldehydes Induce Amyloidogenesis and Dysfunction of Wild-Type Tumor Protein p53 | Chemistry & Biology | 18(7):920-7. | 2011 |
| Aurintricarboxylic acid inhibits the nuclear factor-kB-dependent expression of intercellular cell adhesion molecule-1 and endothelial cell selectin on activated human endothelial cells | Blood Coagulation & Fibrinolysis | 22(2):132-9. | 2011 |
| Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization | Nature Biotechnology | 28(11):1195-202. | 2010 |